Studies on phospholipids. 8. Phospholipids in rat-liver mitochondria and microsomes

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Exchange of phospholipids between liver mitochondria and microsomes in vitro.

A 10% rat liver homogenate in 0.25 M sucrose-10-3 M ethylenediaminetetraacetate was fractionated into mitochondria, microsomes, and a supematant fraction. Liver mitochondria derived from rats injected with leucine-3H and with phosphate-32P or with glycerolJ4C were incubated with nonlabeled microsomes in the presence of supernatant or of sucrose-EDTA. Labeled microsomes were similarly exposed to...

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Rat-liver Mitochondria and Microsomes

Work by Marinetti, Erbland & Stotz (1958) on pig-heart-cell fractions and by Macfarlane, Gray & Wheeldon (1960) on rat-liver-cell fractions have indicated that the mitochondrial and microsomal phospholipids may differ significantly in composition. In view of the results obtained by Collins (1960) and by Collins & Shotlander (1961), showing the widespread occurrence of complex amino-phospholipid...

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Synthesis of Glycerides and Phospholipids in Rat Liver

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Physical Studies of Phospholipids

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ژورنال

عنوان ژورنال: Biochemical Journal

سال: 1961

ISSN: 0306-3283

DOI: 10.1042/bj0790321